Azelaic Acid vs Retinoids: Which Is Right for Your Skin?

Azelaic acid and retinoids are often discussed together, but they serve different purposes. Choosing between them (or knowing when to combine them) depends on your skin, not trends.

How Azelaic Acid Works

Azelaic acid targets inflammation, bacteria and pigment without significantly increasing cell turnover. This makes it gentler and often better tolerated.

How Retinoids Work

Retinoids increase cell turnover and influence collagen production. They can be transformative, but also irritating if used incorrectly.

Key Differences at a Glance

Azelaic Acid

Retinoids

Irritation risk

Low

Moderate–high

Suitable for sensitive skin

Yes

Sometimes

Targets redness

Yes

Not primarily

Speeds cell turnover

No

Yes

Can They Be Used Together?

In some cases, yes, but only with careful spacing and supervision. Layering actives without guidance often leads to barrier damage.

Why Medical Oversight Matters

Choosing the wrong active, or the wrong strength, can worsen skin rather than improve it. This is where personalised advice makes the difference.

There is no “best” active ingredient. The best one for you is the one that suits your skin, used consistently and sensibly.